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doi: 10.1080/01902148.2018.1538396 39 LocasaleJ

One of the main pathways through which oxidative stress causes permanent damage to melanocytes appears to involve the mitochondria, whose DNA is particularly fragile

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Toral M, Robles-Vera I, Romero M, et al

It binds to skeletal muscle cells and activates AMPK, the enzyme responsible for switching cellular metabolism from anabolic (storage) to catabolic (burning) states

Therefore, while both dietary sources and supplements of vitamin C exhibit their benefits, the natural dietary intake is generally preferred over synthetic supplementation for maintaining baseline levels and ensuring a continuous supply of this essential nutrient