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The dual activation of these pathways may provide enhanced protection against beta cell dysfunction and death, potentially offering disease-modifying effects beyond symptomatic glucose control

Further, positive effects of benfotiamine treatment have been shown in several animal models of diabetes

Pr Dreno has served as consultant/received honoraria from Bristol Meyers Squibb, Almirall, Galderma, La Roche Posay, Pierre Fabre and Bioderma

For researchers studying cardiac disease, check out our iPSC-derived cardiomyocytes here: To view or add a comment, sign in Excimer Laser for Plaque Psoriasis: A Systematic Review and Meta-analysis A JDD metaanalysis of 308 nm excimer laser treatment for plaque psoriasis pooled four clinical trials (patients treated twice weekly for greater than or equal to 10 sessions, PASI used as the outcome) and found a statistically significant improvement in disease severity (standardized mean change SMCC -5.94

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Conversely, prolonged elevation of GLUT1 expression can detrimentally impact cartilage by promoting excessive glucose absorption and the accumulation of advanced glycation end-products (3739)