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Furthermore, neural stem cells seem to be more resilient to different death stimuli [47,48,49]

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We speculate that PD-specific C-terminal truncated Syn variants has reduced electrostatic repulsion with negatively charged membranes, enabling additional interactions thereby increasing membrane affinity

doi:10.1111/j.1471-4159.2010.07109.x

In addition, the combination of Exos with antioxidants, iron chelators, or other therapeutic agents could boost their efficacy