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Toward a model-based patient selection strategy for proton therapy: External validation of photon-derived normal tissue complication probability models in a head and neck proton therapy cohort

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doi: 10.1038/s42256-021-00421-z, [DOI] [PMC free article] [PubMed] [Google Scholar] Bak M

It has been proposed that the western diet-induced intestinal ecological dysregulation and the altered intestinal barrier function can induce neuroinflammation, in turn can activate Toll-like receptors, then cause a proinflammatory response and the intestinal glial activation, ultimately contributes to the -synuclein pathology in the pathogenesis of PD (129)

The SARS-CoV-2 virus during infection and persistence prevents the effective brain clearance of excess insoluble amyloid aggregates due to deficient ATP and melatonin as a result of mitochondrial dysfunction

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