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Research has since expanded to cartilage repair after discovery of chondrogenic properties in in vitro and animal models chondrocyte stimulation studies are ongoing

Now the part that matters most, and I cant stress it enough: there are zero published human clinical trials

Direct injection creates foam and shear forces that can denature the peptide before it even dissolves

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Taken together, ER stress plays an important role in neuronal apoptosis induction after TBI, and vitamin B12 inhibits neuronal death by down-regulating ER stress

Published rodent protocols typically use subcutaneous or intraperitoneal injection in saline vehicle, dosed in pulsed courses (for example 1 g/kg daily for 10 days, repeated quarterly)