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Moreover, PGE2 released by tumors upregulates CD73 expression in monocytic MDSCs, leading to increased suppression of T cell activity through elevated adenosine levels

Ongoing support: Dr

doi: 10.1007/BF00296941

For DKD, 590 individuals were included and divided into two groups: 413 patients with T2DM and severe DKD, and 177 participants with more than 10 years of T2DM and no history of DKD

In addition to the breakdown of glucose via glycolysis, cells have the ability to metabolize other substrates, such as lipids and glutamine, which feed into the citric acid cycle and drive OXPHOS