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Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia

DPI is known to increase mitochondrial superoxide production in a dose dependent manner in MNA cells (16)

The mechanisms underlying these effects include enhanced horizontal gene transfer among bacterial communities, particularly fostering the spread of ARGs through oxidative stress, increased membrane permeability, induction of the bacterial SOS response, and upregulation of conjugation-related genes (Figure 2) (Yu K

Wisniewska, M., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Kotzsch, A., Moche, M., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Schutz, P., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Schuler, H., Structural Genomics Consortium (SGC) and RCSB PDB