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Another key area of interest is its potential to reduce inflammatory signaling , particularly through pathways associated with NF-kappaB modulation

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Methylglyoxal spontaneously reacts with glutathione to form a hemithioacetal adduct that is then acted on by glyoxalase-1 (GLO-1) to form S-D-lactoylglutathione and glyoxalase-2 (GLO-2) to form D-lactate

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