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16 patients were 50 years of age

Sci Rep 5 , 8092 (2015)

Targeting DNA repair pathways, the PARP inhibitor Olaparib has also shown potential in regulating ferroptosis

564 Likewise, primary astrocytes prepared from ALS post-mortem samples induced necroptosis of neurones in co-culture, 565 and transplantation of diseased astrocytes into the spinal cord triggered motor deficits and promoted motor neurones degeneration