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This theory has been augmented by several studies that demonstrated increased markers of oxidative stress (by-products of non-enzymatic lipid peroxidation) in children suffering from konzo as well as documentation of deficiencies in micronutrients which are required to maintain effective antioxidant response in konzo-prone populations 18,19

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Wu, D., Xu, H., Chen, J., & Zhang, L

Vitamin B12 status is important for the function of MS

Although reduced protein stability promotes amyloid formation, it alone cannot fully explain disease onset, as pathology is also influenced by external factors