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Thus, 55 of the 57 analyzed metabolic pathways were significantly induced in infected individuals compared to healthy controls, and 39 were significantly more active in patients with severe versus moderate disease

doi: 10.1007/s00432-013-1581-3 88 ZhangZLiNWeiXChenBZhangYZhaoYet al

However, though some studies also reported some plasma biomarkers for brain oxidative damage by analyzing different kinds of samples including F4-Neuroprostanes and F2-Dihomo-Isoprostanes (278), biomarkers in peripheral body fluid samples are still insufficient to identify brain or peripheral oxidative stress at the moment

Islam, Cytotoxicity assessment of zinc oxide nanoparticles on HeLa cell line

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IL-6 is an end-product of the immune activation of these pathways, with increased systemic IL-6 response consistently shown to be associated with the development of long COVID [83]