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The samples were placed in boiling water for 5 min to terminate the reactions

Ab69, which does not inhibit CD38 enzymatic activity, was used as a negative control 36

Serr J, Mathyssen C, Ajime TT, Heigl T, Verlinden L, Maes K, et al

1), including abnormal concentrations of key methylation metabolites such as methionine, S-adenosyl-L-methionine (SAM) and S-adenosyl-L-homocysteine (SAH)