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doi: 10.3390/jcm10184230

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An elevated level of miR-886-3p in FRDA is associated with the downregulation of the FXN gene and the use of anti-miR-886-3p or the HDAC inhibitor 4b alone has been shown to partially reverse FXN gene repression by reducing miR-886-3p levels (Mahishi et al., 2012