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Even ancient peoples, however, realized that the density of gold was greater than that of any other then-known substance

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For a long time, cobalamin has only been known as a widespread organometallic cofactor to many thermally-driven enzymes that catalyse a wide range of processes essential to living organisms, including humans 3

- People with significant liver disease (the 9-month monkey toxicology study showed dose-dependent periportal vacuolation in hepatocytes that the FDA flagged as a possible safety signal)