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Compr Toxicol (Second Edition) 7:475493 Editor information Editors and Affiliations Rights and permissions Copyright information 2021 Springer Nature Singapore Pte Ltd

Serine is critical for cancer progression, fueling macromolecule synthesis (proteins, lipids, nucleotides), antioxidant defense (glutathione production), and one-carbon metabolism (methylation, tRNA formylation) [13]