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Tang, Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism, Nature, vol

Serum and red blood cell folate levels confirm folate deficiency

RNA-induced conformational switching and clustering of G3BP drive stress granule assembly by condensation

adherence to a regular supplementation routine is more important than the specific formulation chosen

This aging mechanism is closely related to various common diseases, including atherosclerosis, hypertension, chronic obstructive pulmonary disease, diabetes, and neurodegenerative disorders ( Current senolytic agents are primarily employed in cancer therapies, such as doxorubicin, trametinib, and cell cycle-targeting drugs like palbociclib ( Although studies have shown that FOXO4-DRI can block the binding of P53 to FOXO4, thereby promoting the apoptosis of senescent cells, the effect of FOXO4-DRI is not limited to alleviating the aging of certain organs