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In 22Rv1 CRPC models, Psa-AR induced 80% degradation of full-length AR, 74% degradation of AR-V7, and 65% depletion of HSP90, markedly outperforming existing PROTACs and small-molecule inhibitor combinations

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Tucker, Kim, Gurzell, et al

For the reconstitution step itself drawing the BAC water and adding it to the vial use a larger 35 mL syringe with a 2327 gauge needle

It works by reducing appetite, improving insulin sensitivity, and encouraging the body to burn fat more efficiently

Mar 2019;8(1):14-21