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Science 2013

doi: 10.1046/j.1463-1326.1999.00028.x 136 RainsJLJainSK

As two negative regulators of p53, MDM2 and MDMX facilitate ferroptosis with or without p53, most likely by altering the lipid profile of cells (Venkatesh et al., 2020), which is confirmed by evidence that with the treatment of MDM2 inhibitor nutlin-3, p53 expression increases and leads to the suppression of X c system inhibitor-induced ferroptosis in HT-1080 cells (Tarangelo et al., 2018)

Likewise, there is data in specific studies that indicate vitamin A correlates significantly with both mitogen-induced pro-inflammatory cytokine (IFN-) and anti-inflammatory cytokine (IL-10) (26)

Furin inhibits epithelial cell injury and alleviates experimental colitis by activating the Nrf 2-Gpx 4 signaling pathway

Crossref Kim S, Chen J, Cheng T, et al