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[40] The liver is a major target organ of GH for this process and is the principal site of IGF-1 production

Since phenomenologically, it is identical to athetosis of central origin, a more appropriate term should be proprioceptive athetosis. Typically involving the fingers or toes, in contrast to central athetosis, the proprioceptive athetosis (pseudoathetosis) usually worsens when the eyes are closed [ 121 ]