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Circulation 124 , 24832490 (2011)

& Kaderali, L

Missing one dose has no meaningful impact on long-term treatment outcomes, but repeatedly injecting during alcohol-induced suppression creates a pattern of suboptimal response that compounds over weeks

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10.1038/s41556-018-0118-z 29 GriffinJ

Mechanistically, IF reduces systemic inflammation, alters the distribution of adipose tissue, and increases thermogenesis, which in turn supports insulin signaling pathways and enhances metabolic flexibility [49]