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These effects can include: Relaxation Euphoria Altered perception Hallucinations Some of the most common side effects of wet drug use include: Anxiety Depression Irritability Learning problems Memory loss Confusion In addition to these psychological side effects, wet drugs may also cause physical symptoms such as: Increased heart rate Elevated blood pressure Profuse sweating Nausea and vomiting Speech problems Loss of coordination and motor skills Stunted growth and development Weight loss Long-term use of wet drugs can lead to addiction and dependence, as well as permanent damage to the brain and other organs

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Alternatively, smoking has been shown to increase the acidity of saliva, generating conditions in which acid-tolerant microbes like Streptococcus are able to thrive