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Indeed, reducing isoleucine by two-thirds in a 21% protein diet was seen to improve multiple aspects of metabolic health and increase longevity substantially (33% median) in males and more modestly (7% median) in females relative to both a control diet and to a diet in which all amino acids were reduced by two-thirds (Yeh et al., 2023)

239 In murine models, enterotoxigenic strain colonization can induce colitis and promote colorectal carcinogenesis through the IL-17R, NF-B, and STAT3 pathways

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Identification of novel allosteric modulators of glutamate transporter EAAT2

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Probiotic supplements reduced fasting insulin, QUICKI, triglycerides, and VLDL, but did not affect other metabolic parameters, including fasting blood glucose, HOMA-IR, additional lipids, body weight, hs-CRP, or DHEAS