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Documentation of side effects helps the care team personalize future dosing or recommend alternative compounds like oral semaglutide if injection tolerance is poor

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Descriptive characteristics of NP and RP groups are shown in Tables 1 and 2

In heart failure mouse models, lipid peroxidation products like 4-HNE and acrolein significantly increase, while pathways for detoxifying these toxic aldehydes decrease, leading to further accumulation and exacerbation of muscle atrophy (61)

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Neuropathologically, PD is defined by the gradual and selective destruction of dopaminergic neurons in the substantia nigra pars compacta (SNpc), resulting in a significant drop in striatal dopamine levels [5]