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The residual unbinding activity after the inhibition of the biorecognition process is likely to result from the forced interaction between the two partners under the experimental design

Given that cancers may alter their metabolism in response to traditional chemotherapy and targeted agents, metabolic inhibitors such as inhibitors of glutamine metabolism are particularly attractive targets in synthetic lethality studies

Such events include, but are not limited to 2 Sidari A, Hill E

Hemmingsson T

In a hyperglycemic environment, non-enzymatic glycation reactions are enhanced, leading to the formation of AGEs (83)

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