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furthermore, measurements in post-mortem conditions are subject to GSH breakdown (Perry et al., 1981), complicating interpretations and comparison to in vivo GSH levels

This balance helps maintain cell survival under toxic conditions (Tan et al., 2006

Gross pathological analysis of the heart was performed

As highlighted by Peine et al

Figure 2 4.1 Key molecular pathways related to neuroinflammation-mediated ferroptosis 4.1.1 Cyclic GMP-AMP synthase/stimulator of interferon genes The stimulator of interferon genes (STING) pathway is activated by double-stranded DNA (dsDNA), which activates the expression of interferon (IFN) via interferon regulatory factor 3 (IRF3) (Liu et al., 2015)

This may suggest that a different mechanism is at play, which could relate to the abnormal immune response present in ME/CFS (311)