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Regarding the bacterial community at the phylum level, Firmicutes emerged as the most abundant taxon, constituting over 70% of the bacterial community (Figure 6A), which is consistent with previous results ( Staphylococcus was the most prevalent across all samples, with relative abundances of 81.39% in T0, 71.65% in T1, 74.29% in T2, and 72.31% in T3

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However, the FDA also made clear that IQOS cannot be endorsed or promoted as safe or "FDA approved." All tobacco products are potentially harmful and addictive, the FDAs statement read at the time