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Furthermore, a preclinical study demonstrated that circulating MPs may impair brain function via immune-mediated vascular occlusion (Huang et al., 2025)

Nature 460823830

Additionally, the metabolism of dopamine by monoamine oxidase (MAO) produces hydrogen peroxide (H 2 O 2 ), which can be converted to highly reactive hydroxyl radicals via Fenton reactions in the presence of transition metals [160]