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Combination and sequential therapies based on ROS tuning This section operationalizes ROS therapy as a time-staged sequence rather than a single intervention

I also outline how treatment options (such as lithium) work in part through homeostatic plasticity. I discuss not only lithium but also the treatment of bipolar with ketamine, different talk therapies, electroconvulsive therapy, transcranial magnetic stimulation, and nutraceuticals, including Omega-3 and Inositol supplementation

This activation results in increased expression of COL1 and -SMA, ultimately contributing to fibrosis

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After three washes with PBT, the sections were incubated with the Alexa Fluor 546-conjugated anti-rabbit (1:600) and Alexa Fluor 488-conjugated anti-mouse (1:400) secondary antibodies for 2 h at room temperature in the dark