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These patients had received standard therapy: surgery to remove their tumors completely, followed by treatment with an immune checkpoint inhibitor (either nivolumab or pembrolizumab)

Anais Brasileiros de Ginecologia, 7 , 2532

and Korytowski, W

Because it is so central to our internal health, many people seek to supplement it, especially as natural production tends to decline with age or increased environmental stress

(1999) 51 Suppl 3:1048

This translational gap motivates an engineering solution: polysaccharide-based nanomedicines that exploit the inflammatory microenvironment (pH, ROS, bacterial glycosidases, receptor overexpression) to achieve spatiotemporally controlled delivery and thereby amplify the very mechanisms delineated above