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The engineered hiPSC-MSCs successfully delivered GPx3 to the liver and ameliorated hepatic injury by inhibiting hepatic senescence [117]

-Synuclein suppresses both the initiation and amplification steps of -synuclein aggregation via competitive binding to surfaces

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It also regulates inflammation suppressing the activation of the nod-like receptor pyrin domain containing protein 3 (NLRP3) inflammasome and the subsequent caspase-1 activation and interleukin 1 (IL-1) secretion (Youm et al., 2015)

Abstract Bcr-Abl transformation leads to chronic myeloid leukemia (CML)

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