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The imbalance between the availability of lipids in the liver and their metabolism (e.g., catabolism and transport) contributes to hepatic steatosis, a reversible condition that occurs in both ALD and MASLD that can progress to advanced stages, such as alcoholic steatohepatitis and MASH that ultimately can culminate in HCC [114116]

It plays a fundamental role in maintaining cellular health, primarily by serving as a potent antioxidant and participating in various enzymatic reactions throughout the body

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6.4.3 Structural silencing and interaction mapping Advancements in drug-target interaction mapping, facilitated by AI-driven docking and high-resolution cryo-electron microscopy, enable the intentional silencing of binding sites