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Conclusion: Spironolactone therapy is associated with reduced alcohol use and incident ALD in patients with AUD and may offer a novel therapeutic strategy in limiting the development of ALD in high-risk patients

By sensing changes in the intracellular ATP/AMP ratio, AMPK activates FAO and mitochondrial respiration, enhancing cellular adaptation to energy deprivation [30, 31]

They play both structural and functional roles, including electron transfer, redox sensing, and as structural modules

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Leucoanthocyanidins as intermediates in anthocyanidin biosynthesis in flowers of Matthiola incana R