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Additionally, the use of immunofluorescence assays to detect H2AX foci offers a powerful approach for identifying double-strand breaks in DNA, a direct consequence of ROS-mediated damage

Inertial cavitation leads to the eventual collapse of the microbubbles, creating jets, shock waves, or other inertial effects that have the potential to damage the brain parenchyma and the bloodbrain barrier[179]

Recent advances have substantially advanced our understanding of the complex and essential chemistry of biological sulfur-containing molecules

Recent experimental work also supports these findings

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PMC 4894846