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A possible implication of MCT9 in some cancer types was reported: the transporter seems to be a good diagnostic target to distinguish benign from malignant adrenocortical tumors (Fernandez-Ranvier et al., 2008)

The effective blood-brain barrier mechanism impeding the transport of monoamines has been attributed to both the presence of tight junctions cementing adjacent endothelial cells of the cerebral capillary walls, along with high concentrations of dopa decarboxylase and monoamine oxidase (MAO) in the cerebral capillary endothelium (Bertler et al, 1966

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Taken together, it is important to realize that at present no animal model represents the full clinical situation perfectly because of interspecies differences and inevitable differences between the conditions created in animals and those observed in human CIPN

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