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In addition, unextractable radioactivity observed in human plasma protein pellet and the detection of an LY3202626-dimedone adduct in human liver microsomal incubations supplemented with NADPH and dimedone suggested that a reactive sulfenic acid intermediate might be formed through bioactivation and subsequently react with sulfhydryl moiety of plasma proteins to form covalent adducts

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Each dot represents one individual field of view ( d , i , j , k ) or a biological replicate ( a , e h )

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Glycolytic ATP alone, with its limited production capacity, is unlikely to be sufficient to power ion pumping required for the maintenance of ion gradient and membrane potential (Hall et al., 2012), but it may nevertheless play an important role in fast refueling