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Notably, in contrast to numerous studies previously discussed where CBD decreased inflammation through reduced NO production and NOS activity, this study demonstrated that CBD administration was associated with elevated levels of inflammatory markers, including iNOS

doi: 10.1136/annrheumdis-2017-212647 25 VealeDJOrrCFearonU

It is expressed in ~60-70% of mouse RGCs, 100% of Mller cells (Figure 18A) and the majority of trabecular and corneal epithelial cells (70, 113, 132), with some RGCs sharing TRPV4 expression with the cognate TRPV1 channel (Figure 18B) (70, 128)