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The regulation of senescence by AMPK mainly links to the SIRTs family, and the intracellular signals generated by AMPK are important core substances that inhibit the senescence of cardiomyocytes

Marzagalli M, Ebelt ND, Manuel ER

Finally, the review identifies persistent challenges including phytochemical standardization and the translational gap between preclinical and clinical research, and proposes future research directions focused on rigorous clinical trials, mechanistic studies and sustainable exploitation within a circular bioeconomy framework

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The structure-based design of Mdm2/Mdmx-p53 inhibitors gets serious

Investigations showed that the source of GHB was brightly colored beads, which were coated with a glue-based product made from BD