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Biotech Histochem 83: 103130 [DOI] [PMC free article] [PubMed] [Google Scholar] Rothenberg SM, Concannon K, Cullen S, Boulay G, Turke AB, Faber AC, Lockerman EL, Rivera MN, Engelman JA, Maheswaran S et al (2015) Inhibition of mutant EGFR in lung cancer cells triggers SOX2FOXO6dependent survival pathways

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Accordingly, the fluorescence of NADH is lost when it is oxidized to NAD + on complex I, allowing to follow the fate of the molecule and measure activity of complex I

This mechanism reduces endotoxin translocation and inhibits activation of the hepatic TLR4/NF-B inflammatory signaling pathway induced by LPS from Enterobacteriaceae

The top ten binding targets with the highest scores were analyzed in this study