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Accumulation of 8-OHdG, induced by hydroxyl radicals, serves as a marker of DNA damage and can be detected in both liver tissue and urine, correlating with disease activity

This can be done for various reasons, including to improve the appearance of scars, hyperpigmentation, or other skin blemishes or to even out the skin tone

f , Representative images (left panel) and quantification (right panel) of CD45/p21 co-staining in ID8 Trp53 / omental tumours treated with cisplatin

Hopfner et al., 2017), and increase in Akkermansia /Verrucomicrobiaceae (Keshavarzian et al., 2015

Sidthilaw et al., 2022)

These efflux pumps are primarily mediated by ATP-binding cassette (ABC) transporters