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Description

In CNS neuroinflammation, TSPO is highly expressed on activated microglia, and to a lesser extent on astrocytes and macrophages

The four-week titration between dose increases was specifically designed to minimize these effects by allowing GI adaptation before increasing the dose further

JAMA 300 , 23792388 (2008)

In conclusion, VLDLR suppresses fibrosis by attenuating TGF 2 -induced metabolic reprogramming, and CPT1A is a potential target for treating subretinal fibrosis