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Nat Rev Neurosci

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Although 18:0 also accumulates in the fat-5 and fat-7 mutants grown on nhr-80(RNAi), the extent of 18:0 accumulation is not as dramatic as observed in fat-6 (Figure 7B) and they do not show a synthetic lethality (Figure 7A)

and Aaron, C

The current consensus theory about the origin of N -trimethyllysine in mammals is that mammals utilise lysosomal or proteasomal degradation of proteins containing N -trimethyllysine residues as starting point for carnitine biosynthesis