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In the next section, studies performed to evaluate the effect of HMOX1 modulation in IBD will be discussed

Glycolysis and rheumatoid arthritis

16 However, the large FAZST trial found no significant benefit in an unselected population

Efferocytosis of apoptotic neutrophils reprogrammed macrophage mitochondrial metabolism through mieloperoxidase-dependent UCP2, which increases proton conductance in the inner mitochondrial membrane, thereby impairing reactive oxygen species (mtROS) production in response to bacteria