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Reviewed by Written by Published Read Time 89 minutes Published Read Time 89 minutes What Happened The Announcement Explained What Happened The Announcement Explained For the millions of patients who relied on physician-prescribed peptide therapies and the clinicians who prescribed them 2023 was a hard year

Patients have used it for decades in Eastern Europe without toxicity

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Signs of developing tolerance that community sources describe (typically weeks 4-6): appetite suppression weakening, the energy boost diminishing, return of cravings

& Banerjee, S

Competing interests The authors declare no conflict of interest