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WJ-MSCs, which have low immunogenicity and immunomodulatory potential, have gained great interest in clinical application ( To further enhance the effectiveness of MSCs, many engineered cells have been developed that overexpress key proteins that promote proliferation and matrix production in IVD cells, including Bone morphogenetic protein 7 (BMP7) (Xu et al., 2016), Bone morphogenetic protein 2 (BMP2) (Wei et al., 2016), superoxide dismutase 2 (Sod2) and catalase (Cat) (Xiao et al., 2021)

Tissue infiltration used Spurrs epoxy resin via a 3:1 acetone-resin mixture (4 h), 1:1 transition (8 h), and pure resin (24 h under vacuum), followed by polymerization at 60 C for 48 h under nitrogen

Considering the differences in the baseline characteristics between PD patients and HC, propensity score matching (PSM) was applied for identifying a cohort with similar baseline characteristics 28

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When Sry HC male mice were evaluated and compared with Sry fl/fl mice, we found that in contrast to the exacerbation of liver damage caused by SRY overexpression, hepatocyte-specific SRY deficiency substantially decreased serum ALT and AST levels (Fig

10.1016/j.fshw.2015.02.001 46 PhaniendraA.JestadiD