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In a mouse PD model, Mucuna pruriens seed extract (rich in natural LDOPA plus other constituents) was found to decrease levels of interleukin6 (IL6) and TGF1 in the brain, similar to pure levodopa [47]

An engineered subcutaneously implanted catheter pump to enhance delivery of topotecan into the brain was examined to evaluate its safety, efficacy, and biological effects in a patient with recurrent GBM, demonstrating a promising outcome

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TCM herbal therapies have been used traditionally to promote circulation, resolve blood stasis, and tonify the heart in these conditions

These models are particularly relevant for studying myocardial reperfusion injury and coronary artery disease, as well as for exploring the pathophysiology of I/R injury in other organs such as the liver and kidney

A novel polysaccharide obtained from Craterellus cornucopioides enhances immunomodulatory activity in immunosuppressive mice models via regulation of the TLR4-NF-B pathway