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In vivo studies of AML xenografted mice showed that the ADC significantly depleted bone marrow HSPCs and peripheral blood myeloid cells, leading to ADC-treated mice showing an extended survival versus untreated and isotype control

Sodium Retention : Certain inflammatory pathways can increase sodium retention in the kidneys, expanding blood volume and raising pressure

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Rather than stimulating growth hormone release, this peptide is actually a modified fragment of the growth hormone molecule itself, specifically amino acids 177 through 191 of the human GH sequence

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