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Research Applications Appetite and feeding behavior: The established primary application characterizing NPY/AgRP-mediated orexigenic signaling in preclinical models using the compound most reliably activating those circuits Energy homeostasis: Ghrelins role in energy balance, adipogenesis, and metabolic adaptation during caloric restriction

Use of growth hormone, IGF-I, and insulin for anabolic purpose: Pharmacological basis, methods of detection, and adverse effects

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Special caution should be taken when prescribing antihistamines and antidepressants to patients with cancerparticularly in the elderlyto avoid oversedation

Low plasma insulin-like growth factor-1 levels are associated with reduced insulin sensitivity and increased insulin secretion in nondiabetic subjects

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