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Lancet 397:23612371 Martin T, Mikhael J, Hajek R, Kim K, Suzuki K, Hulin C et al (2020) Depth of response and response kinetics of isatuximab plus carfilzomib and dexamethasone in relapsed multiple myeloma: IKEMA interim analysis

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Research shows the risk increases after 6+ months of therapy, particularly in those with plant-based diets or existing digestive conditions