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developed EGFR-targeted CRISPR-LNPs against PLK1 (sgPLK1-cLNPs) that led to selective uptake into disseminated ovarian cancer cells and facilitated up to 80% gene editing in vivo , significantly inhibiting tumor growth and improving survival by 80% in a mouse model (Rosenblum et al., 2020)

Whole egg, but not egg white, ingestion induces mTOR colocalization with the lysosome after resistance exercise

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Supports energy levels Contributes to normal energy metabolism and helps reduce tiredness and fatigue

Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier

These effects included reduction of vWF multimer size, removal of ULVWF strings from the endothelial surface, and marked shortening of the time to reestablish normal blood flow in the microvasculature of ADAMTS13-deficient mice challenged to secrete vWF