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The second bottleneck is the crew : even with a good supply line, repair cells (fibroblasts, and others) have to physically migrate into the wound and rebuild the matrix

presumably as a control system for their enzymatic activity or protein-protein interaction (Moretti et al., 2018)

A lack of ferritin leads to an increase in the intracellular free iron concentration and ROS accumulation, making cardiomyocytes more susceptible to ferroptosis 26

Neuroscience 2014;281:68-76

NPJ Biofilms Microbiomes 143 ThomsenR

For example, in rats fed an atherosclerotic diet, the administration of 0.2% green tea extract (Polyphenon ) resulted in a significant reduction in serum inflammatory markers (CRP) (103)